Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice

Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice

Apolipoprotein E ε4 (APOE4) is the primary genetic risk factor for the late-onset form of Alzheimer’s disease (AD). Although the reason for this association is not completely understood, researchers have uncovered numerous effects of APOE4 expression on AD-relevant brain processes, including amyloid...

Full description

Bibliographic Details
Main Authors: Area-Gomez, E. (Author), Ashok, A. (Author), Chan, R.B (Author), Di Paolo, G. (Author), Duff, K.E (Author), McIntire, L.B (Author), Miranda, A.M (Author), Nuriel, T. (Author), Oliveira, T.G (Author), Xu, Y. (Author), Zhou, B. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Subjects:
amyloid beta protein
Amyloid beta-Peptides
animal
Animals
apolipoprotein E3
Apolipoprotein E3
apolipoprotein E4
Apolipoprotein E4
entorhinal cortex
Entorhinal Cortex
genetics
lipidomics
Lipidomics
metabolism
Mice
mouse
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items