5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction
Blockade of N-methyl-D-aspartate receptors (NMDAR) is known to augment cortical serotonin 2A receptors (5-HT2ARs), which is implicated in psychosis. However, the pathways from NMDAR hypofunction to 5-HT2AR up-regulation are unclear. Here we addressed in mice whether genetic deletion of the indispens...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |