Non-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7

Non-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7

Drug resistance is responsible for castration-resistant prostate cancer (CRPC)-associated mortality. While ATP binding cassette subfamily C member 5 (ABCC5) has been reported to regulate multiple drug resistance, its drug-efflux function may not be the main reason underlying resistance to enzalutami...

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Main Authors: Chen, H. (Author), Chen, S. (Author), Ding, J. (Author), Du, K. (Author), Ji, H. (Author), Luo, J. (Author), Shi, B. (Author), Yin, Y. (Author), Yu, Y. (Author), Zhang, X. (Author), Zheng, X. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
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