Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession

Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession

PKM2 is an important regulator of the aerobic glycolysis that plays a vital role in cancer cell metabolic reprogramming. In general, Trib2 is considered as a “pseudokinase”, contributing to different kinds of cancer. However, the detailed roles of TRIB2 in regulating cancer metabolism by PKM2 remain...

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Bibliographic Details
Main Authors: Hu, J.-X (Author), Li, Y.-J (Author), Li, Y.-M (Author), Liang, D.-M (Author), Liang, Y. (Author), Liu, Y.-R (Author), Song, D.-D (Author), Sun, H.-F (Author), Wang, P. (Author), Wang, R.-R (Author), Xie, S.-Y (Author), Yan, Y.-F (Author), Yang, Z. (Author), Zhang, M.-L (Author), Zhao, Y.-L (Author), Zheng, H.-F (Author)
Format: Article
Language:English
Published: Springer Nature 2022
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