Spatiotemporal regulation of insulin signaling by liquid–liquid phase separation

Spatiotemporal regulation of insulin signaling by liquid–liquid phase separation

Insulin signals through its receptor to recruit insulin receptor substrates (IRS) and phosphatidylinositol 3-kinase (PI3K) to the plasma membrane for production of phosphatidylinositol-3,4,5-trisphosphate (PIP3) from phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], which consequently activates pro...

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Bibliographic Details
Main Authors: Chen, J. (Author), Chen, Q. (Author), Chen, S. (Author), Feng, W. (Author), Liang, D. (Author), Liu, M. (Author), Ouyang, Q. (Author), Quan, C. (Author), Wang, Q. (Author), Wang, R. (Author), Zhou, K. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
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