Modification of BRCA1-associated breast cancer risk by HMMR overexpression

Modification of BRCA1-associated breast cancer risk by HMMR overexpression

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Breast cancer risk for carriers of BRCA1 pathological variants is modified by genetic factors. Genetic variation in HMMR may contribute to this effect. However, the impact of risk modifiers on cancer biology remains undetermined and the biological basis of increased risk is poorly understood. Here,...

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Main Authors: Baiges, A. (Author), Blommaert, E. (Author), Brunet, J. (Author), Chen, K. (Author), de Garibay, G.R (Author), Eaves, C.J (Author), Espín, R. (Author), Extremera, A.I (Author), García, N. (Author), Garrido-Utrilla, A. (Author), Gómez, A. (Author), Hakem, R. (Author), He, Z. (Author), Herranz, C. (Author), Khokha, R. (Author), Lange, P.F (Author), Lázaro, C. (Author), Li, R. (Author), Lorentzian, A. (Author), Mateo, F. (Author), Maxwell, C.A (Author), McCloskey, C. (Author), Mei, L. (Author), Mirallas, O. (Author), Palomero, L. (Author), Petit, A. (Author), Pujana, M.A (Author), Soler-Monsó, M.T (Author), Tan, S. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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