Molecular basis of antibiotic self-resistance in a bee larvae pathogen

Paenibacillus larvae, the causative agent of the devastating honey-bee disease American Foulbrood, produces the cationic polyketide-peptide hybrid paenilamicin that displays antibacterial and antifungal activity. Its biosynthetic gene cluster contains a gene coding for the N-acetyltransferase PamZ....

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Bibliographic Details
Main Authors: Bulatov, T. (Author), Dang, T. (Author), Ebeling, J. (Author), Genersch, E. (Author), Gensel, S. (Author), Göbel, J. (Author), Loll, B. (Author), Mainz, A. (Author), Müller, S. (Author), Skobalj, R. (Author), Süssmuth, R.D (Author), Wahl, M.C (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher