Structural basis for the synthesis of the core 1 structure by C1GalT1

C1GalT1 is an essential inverting glycosyltransferase responsible for synthesizing the core 1 structure, a common precursor for mucin-type O-glycans found in many glycoproteins. To date, the structure of C1GalT1 and the details of substrate recognition and catalysis remain unknown. Through biophysic...

Full description

Bibliographic Details
Main Authors: Clausen, H. (Author), Coelho, H. (Author), Compañón, I. (Author), Corzana, F. (Author), González-Ramírez, A.M (Author), Grosso, A.S (Author), Hurtado-Guerrero, R. (Author), Marcelo, F. (Author), Narimatsu, Y. (Author), Yang, Z. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher