Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms

SCCmec is a large mobile genetic element that includes the mecA gene and confers resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus (MRSA). There is evidence that SCCmec disseminates among staphylococci, but the transfer mechanisms are unclear. Here, we show that two-c...

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Bibliographic Details
Main Authors: Higashide, M. (Author), Maree, M. (Author), Morikawa, K. (Author), Msadek, T. (Author), Ohniwa, R.L (Author), Thi Nguyen, L.T (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher