Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2

Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2

The global spread of SARS-CoV-2 led to major economic and health challenges worldwide. Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide insights into the virus pathogenesis, and facilitate the development of novel therapeutics. Here, employing a genome-scal...

Full description

Bibliographic Details
Main Authors: Aftalion, M. (Author), Bercovich-Kinori, A. (Author), Beth-Din, A. (Author), Chitlaru, T. (Author), Cohen, O. (Author), Cohen-Gihon, I. (Author), Elia, U. (Author), Falach, R. (Author), Finkel, Y. (Author), Israeli, M. (Author), Israeli, O. (Author), Israely, T. (Author), Kliker, L. (Author), Mandelboim, M. (Author), Nemet, I. (Author), Paran, N. (Author), Rotem, S. (Author), Stern-Ginossar, N. (Author), Yahalom-Ronen, Y. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items