Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach

The rising prevalence of childhood obesity has been postulated as an explanation for the increasing rate of individuals diagnosed with type 1 diabetes (T1D). In this study, we use Mendelian randomization (MR) to provide evidence that childhood body size has an effect on T1D risk (OR = 2.05 per chang...

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Bibliographic Details
Main Authors: Cho, Y. (Author), Crouch, D.J.M (Author), Cucca, F. (Author), Davey Smith, G. (Author), Fang, S. (Author), Hazelwood, E. (Author), Inshaw, J.R.J (Author), Morales-Berstein, F. (Author), Power, G.M (Author), Rich, S.S (Author), Richardson, T.G (Author), Robertson, C.C (Author), Sidore, C. (Author), Todd, J.A (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher