Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF

Enhancer RNAs (eRNAs) are long non-coding RNAs that originate from enhancers. Although eRNA transcription is a canonical feature of activated enhancers, the molecular features required for eRNA function and the mechanism of how eRNAs impinge on target gene transcription have not been established. Th...

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Bibliographic Details
Main Authors: Brennecke, T. (Author), Gorbovytska, V. (Author), Götze, M. (Author), Kang, K. (Author), Kim, S.-K (Author), Kim, T.-K (Author), Kuhn, C.-D (Author), Kuybu, F. (Author), Leitner, A. (Author), Pittroff, A. (Author), Schneider, L.-M (Author), Um, D. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher