Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus

Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus

Most structurally characterized broadly neutralizing antibodies (bnAbs) against influenza A viruses (IAVs) target the conserved conformational epitopes of hemagglutinin (HA). Here, we report a lineage of naturally occurring human antibodies sharing the same germline gene, VH3-48/VK1-12. These antibo...

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Main Authors: Chen, S. (Author), Cong, Y. (Author), Ding, J. (Author), Dong, X. (Author), Jin, M. (Author), Li, L. (Author), Li, Z. (Author), Ling, Z. (Author), Liu, C. (Author), Lu, X. (Author), Ma, L. (Author), Qian, Z. (Author), Sun, B. (Author), Sun, X. (Author), Tang, S. (Author), Wang, D. (Author), Wang, F. (Author), Wang, W. (Author), Wangmo, S. (Author), Yang, Z. (Author), Yi, C. (Author), Zhang, Y. (Author), Zhang, Z. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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