A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis

A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis

We describe a precision medicine workflow, the integrated single nucleotide polymorphism network platform (iSNP), designed to determine the mechanisms by which SNPs affect cellular regulatory networks, and how SNP co-occurrences contribute to disease pathogenesis in ulcerative colitis (UC). Using SN...

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Bibliographic Details
Main Authors: Bender, A. (Author), Bohar, B. (Author), Brooks-Warburton, J. (Author), Carding, S.R (Author), Fazekas, D. (Author), Hall, L.J (Author), Kapuy, O. (Author), Korcsmaros, T. (Author), Madgwick, M. (Author), Modos, D. (Author), Parkes, M. (Author), Sudhakar, P. (Author), Szalay-Beko, M. (Author), Thomas, J.P (Author), Tremelling, M. (Author), Vermeire, S. (Author), Verstockt, B. (Author), Watson, A. (Author), Zoufir, A. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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