Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination

Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination

Remyelination failure in multiple sclerosis (MS) contributes to progression of disability. The deficient repair results from neuroinflammation and deposition of inhibitors including chondroitin sulfate proteoglycans (CSPGs). Which CSPG member is repair-inhibitory or alters local inflammation to exac...

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Bibliographic Details
Main Authors: Buehner, B. (Author), Dong, Y. (Author), Geurts, J. (Author), Ghorbani, S. (Author), Jain, R. (Author), Jelinek, E. (Author), Karimi-Abdolrezaee, S. (Author), Kaushik, D.K (Author), Li, C. (Author), Ling, C.-C (Author), Lozinski, B.M (Author), Sarkar, S. (Author), Schenk, G.J (Author), Strijbis, E.M (Author), Wight, T.N (Author), Yong, V.W (Author), Zhang, P. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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