Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer

Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer

The genetic basis of colorectal cancer (CRC) and its clinical associations remain poorly understood due to limited samples or targeted genes in current studies. Here, we perform ultradeep whole-exome sequencing on 1015 patients with CRC as part of the ChangKang Project. We identify 46 high-confident...

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Main Authors: Chen, G. (Author), Chen, S. (Author), Chen, Y.-X (Author), Ding, P.-R (Author), He, M.-M (Author), Huang, T. (Author), Huang, Y.-S (Author), Jia, W.-H (Author), Jiang, T.-J (Author), Jing, Y. (Author), Li, L.-R (Author), Li, Y.-H (Author), Long, R. (Author), Lu, Z.-H (Author), Luo, H.-Y (Author), Mai, Z.-J (Author), Pan, Z.-Z (Author), Pu, H.-Y (Author), Qiu, M.-Z (Author), Wang, F. (Author), Wang, Y.-N (Author), Wang, Z.-X (Author), Wu, C.-Y (Author), Wu, Q.-N (Author), Xu, M. (Author), Xu, R.-H (Author), Yao, Y.-C (Author), Zeng, Z.-L (Author), Zhang, D.-S (Author), Zhang, J. (Author), Zhang, X. (Author), Zhao, Q. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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