The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy

Decline in skeletal muscle cell size (myofiber atrophy) is a key feature of cancer-induced wasting (cachexia). In particular, atrophy of the diaphragm, the major muscle responsible for breathing, is an important determinant of cancer-associated mortality. However, therapeutic options are limited. He...

Full description

Bibliographic Details
Main Authors: Demontis, F. (Author), Fan, Y. (Author), Gordon, B. (Author), Graca, F.A (Author), Hunt, L.C (Author), Labelle, M. (Author), Quarato, G. (Author), Rai, M. (Author), Stephan, A. (Author), Wang, R. (Author), Wang, Y.-D (Author), Xu, B. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Subjects:
Online Access:View Fulltext in Publisher