The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy
Decline in skeletal muscle cell size (myofiber atrophy) is a key feature of cancer-induced wasting (cachexia). In particular, atrophy of the diaphragm, the major muscle responsible for breathing, is an important determinant of cancer-associated mortality. However, therapeutic options are limited. He...
Main Authors: | Demontis, F. (Author), Fan, Y. (Author), Gordon, B. (Author), Graca, F.A (Author), Hunt, L.C (Author), Labelle, M. (Author), Quarato, G. (Author), Rai, M. (Author), Stephan, A. (Author), Wang, R. (Author), Wang, Y.-D (Author), Xu, B. (Author) |
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Format: | Article |
Language: | English |
Published: |
Nature Research
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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