Developmental mRNA m5C landscape and regulatory innovations of massive m5C modification of maternal mRNAs in animals

Developmental mRNA m5C landscape and regulatory innovations of massive m5C modification of maternal mRNAs in animals

m5C is one of the longest-known RNA modifications, however, its developmental dynamics, functions, and evolution in mRNAs remain largely unknown. Here, we generate quantitative mRNA m5C maps at different stages of development in 6 vertebrate and invertebrate species and find convergent and unexpecte...

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Bibliographic Details
Main Authors: Cai, B. (Author), Chen, W. (Author), Ding, C. (Author), Ge, W. (Author), He, X. (Author), Huang, T. (Author), Li, S. (Author), Liu, J. (Author), Xu, Y. (Author), Xue, M. (Author), Zhang, L. (Author), Zhang, R. (Author), Zhang, Y. (Author), Zhao, T. (Author), Zhao, X. (Author), Zhou, C. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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