High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control
DNA replication initiates from replication origins firing throughout S phase. Debate remains about whether origins are a fixed set of loci, or a loose agglomeration of potential sites used stochastically in individual cells, and about how consistent their firing time is. We develop an approach to pr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Research
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |