Renal UTX-PHGDH-serine axis regulates metabolic disorders in the kidney and liver

Renal UTX-PHGDH-serine axis regulates metabolic disorders in the kidney and liver

Global obesity epidemics impacts human health and causes obesity-related illnesses, including the obesity-related kidney and liver diseases. UTX, a histone H3K27 demethylase, plays important roles in development and differentiation. Here we show that kidney-specific knockout Utx inhibits high-fat di...

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Bibliographic Details
Main Authors: Chen, H. (Author), Chen, Y. (Author), Huang, K. (Author), Huang, Y. (Author), Liu, C. (Author), Su, H. (Author), Wang, Q. (Author), Wang, S. (Author), Xie, Y. (Author), Xiong, M. (Author), Yang, D. (Author), Yue, J. (Author), Zeng, X. (Author), Zhang, Y. (Author), Zheng, L. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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