An in situ hydrogel-mediated chemo-immunometabolic cancer therapy

Metabolic reprogramming of the tumor microenvironment (TME) and poor immunogenicity are two of the challenges that cancer immunotherapies have to overcome for improved clinical benefits. Among various immunosuppressive metabolites that keep anti-tumor immunity in check, the tryptophan catabolite kyn...

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Bibliographic Details
Main Authors: Caserto, J.S (Author), Chen, J. (Author), Ma, M. (Author), Wang, B. (Author), Wang, X. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher