Clinical relevance of pathogenic germline variants in mismatch repair genes in Chinese breast cancer patients

Clinical relevance of pathogenic germline variants in mismatch repair genes in Chinese breast cancer patients

The prevalence and clinical relevance of pathogenic germline variants in MMR genes have not been investigated in large series of breast cancers. In this study, we screened the germline variants in MMR genes in 8085 consecutive Chinese breast cancer patients, and investigated the MMR/PD-L1 protein ex...

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Main Authors: Ding, X. (Author), Hu, L. (Author), Li, Z. (Author), Liu, J. (Author), Liu, Y. (Author), Qu, Z. (Author), Sun, J. (Author), Wan, Q. (Author), Wang, Y. (Author), Xie, Y. (Author), Xu, Y. (Author), Yao, L. (Author), Zang, F. (Author), Zhang, J. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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