Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer

Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer

Fragmentation patterns of plasma cell-free DNA (cfDNA) are known to reflect nucleosome positions of cell types contributing to cfDNA. Based on cfDNA fragmentation patterns, the deviation in nucleosome footprints was quantified between diagnosed ovarian cancer patients and healthy individuals. Multin...

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Main Authors: Bourne, T. (Author), Braicu, E.I (Author), Busschaert, P. (Author), Concin, N. (Author), Coosemans, A. (Author), Froyman, W. (Author), Han, S.N (Author), Heremans, R. (Author), Lambrechts, D. (Author), Landolfo, C. (Author), Loverix, L. (Author), Neven, P. (Author), Olbrecht, S. (Author), Timmerman, D. (Author), Van Calster, B. (Author), Van Gorp, T. (Author), Van Nieuwenhuysen, E. (Author), Vanderstichele, A. (Author), Venken, T. (Author), Vergote, I. (Author), Wimberger, P. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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