Calycosin prevents bone loss induced by hindlimb unloading

Calycosin prevents bone loss induced by hindlimb unloading

Bone loss induced by microgravity exposure seriously endangers the astronauts’ health, but its countermeasures still have certain limitations. The study aims to find potential protective drugs for the prevention of the microgravity-induced bone loss. Here, we utilized the network pharmacology approa...

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Bibliographic Details
Main Authors: Deng, X. (Author), Gao, S. (Author), Huai, Y. (Author), Jin, X. (Author), Lai, L. (Author), Li, F. (Author), Liang, X. (Author), Miao, Z. (Author), Qian, A. (Author), Qiu, W. (Author), Ru, K. (Author), Wang, H. (Author), Zhang, J. (Author), Zhang, W. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Subjects:
Bone
Bone loss
Bone remodelling
Hind limbs
Hindlimb unloading
Interaction networks
Manned space flight
Microgravity
Microgravity processing
Natural compounds
Network pharmacologies
Potential effects
Rat model
Rats
Topological characteristics
Unloading
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