Toward therapeutic electrophysiology: beta-band suppression as a biomarker in chronic local field potential recordings

Toward therapeutic electrophysiology: beta-band suppression as a biomarker in chronic local field potential recordings

Adaptive deep brain stimulation (aDBS) is a promising concept for feedback-based neurostimulation, with the potential of clinical implementation with the sensing-enabled Percept neurostimulator. We aim to characterize chronic electrophysiological activity during stimulation and to validate beta-band...

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Bibliographic Details
Main Authors: Al-Fatly, B. (Author), Bahners, B.H (Author), Denison, T. (Author), Faust, K. (Author), Feldmann, L.K (Author), Florin, E. (Author), Krauss, J.K (Author), Kühn, A.A (Author), Lofredi, R. (Author), Neumann, W.-J (Author), Nikolov, P. (Author), Roediger, J. (Author), Saryyeva, A. (Author), Schneider, G.-H (Author), Schnitzler, A. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Subjects:
adult
aged
Article
beta rhythm
biological marker
bradykinesia
brain depth stimulation
clinical article
cognition
cohort analysis
computer assisted emission tomography
computer assisted tomography
controlled study
disease duration
disease severity
dopaminergic system
electroencephalography
electrophysiology
fatigue
female
frequency analysis
human
local field potential
male
middle aged
motor performance
nerve stimulation
predictive value
spreading cortical depression
subthalamus
task performance
Unified Parkinson Disease Rating Scale
velocity
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