Integrative computational approach identifies drug targets in CD4+ T-cell-mediated immune disorders

CD4+ T cells provide adaptive immunity against pathogens and abnormal cells, and they are also associated with various immune-related diseases. CD4+ T cells’ metabolism is dysregulated in these pathologies and represents an opportunity for drug discovery and development. Genome-scale metabolic model...

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Bibliographic Details
Main Authors: Amin, R. (Author), Barberis, M. (Author), Bennett, S.J (Author), Ciurej, A. (Author), Helikar, T. (Author), Lichter, B. (Author), Moore, R. (Author), Puniya, B.L (Author), Shah, A.R (Author)
Format: Article
Language:English
Published: Nature Research 2021
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Online Access:View Fulltext in Publisher