Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery
In this study, we integrate the outcomes of co-expression network analysis with the human interactome network to predict novel putative disease genes and modules. We first apply the SWItch Miner (SWIM) methodology, which predicts important (switch) genes within the co-expression network that regulat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Research
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |