Predicted ‘wiring landscape’ of Ras-effector interactions in 29 human tissues

Ras is a plasma membrane (PM)-associated signaling hub protein that interacts with its partners (effectors) in a mutually exclusive fashion. We have shown earlier that competition for binding and hence the occurrence of specific binding events at a hub protein can modulate the activation of downstre...

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Bibliographic Details
Main Authors: Catozzi, S. (Author), Halasz, M. (Author), Kiel, C. (Author)
Format: Article
Language:English
Published: Nature Research 2021
Subjects:
Online Access:View Fulltext in Publisher