Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma

Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma

We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our results provide insights into the manifested effects of ea...

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Bibliographic Details
Main Authors: Adissu, H.A (Author), Borchers, C.H (Author), Flenniken, A.M (Author), Ganguly, M. (Author), Lloyd, K.C.K (Author), McKerlie, C. (Author), Michaud, S.A (Author), Mohammed, Y. (Author), Nutter, L.M.J (Author), Pětrošová, H. (Author), Schibli, D. (Author), Yang, J. (Author)
Format: Article
Language:English
Published: Nature Research 2021
Subjects:
animal
Animals
female
Female
genetics
knockout mouse
male
Male
Mice
Mice, Knockout
mouse
plasma
Plasma
proteome
Proteome
proteomics
Proteomics
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