Using predictive machine learning models for drug response simulation by calibrating patient-specific pathway signatures

The utility of pathway signatures lies in their capability to determine whether a specific pathway or biological process is dysregulated in a given patient. These signatures have been widely used in machine learning (ML) methods for a variety of applications including precision medicine, drug repurp...

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Bibliographic Details
Main Authors: Bharadhwaj, V.S (Author), Domingo-Fernández, D. (Author), Golriz Khatami, S. (Author), Hofmann-Apitius, M. (Author), Kodamullil, A.T (Author), Mubeen, S. (Author)
Format: Article
Language:English
Published: Nature Research 2021
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