An adjuvanted zoster vaccine elicits potent cellular immune responses in mice without QS21

Herpes zoster (HZ) is caused by reactivation of latent varicella-zoster virus (VZV) when VZV-specific cellular immunity is insufficient to control reactivation. Currently, Shingrix, which contains the VZV gE protein and GSK’s AS01B adjuvant composed of liposomes formulated with cholesterol, monophos...

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Bibliographic Details
Main Authors: Carter, D. (Author), Casper, C. (Author), Hong, S.J (Author), Kim, J. (Author), Lee, A. (Author), Lee, S. (Author), Nam, H.J (Author), Reed, S.G (Author), Shin, E.-C (Author), Simeon, G. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher