A DNA vaccine targeting VEE virus delivered by needle-free jet-injection protects macaques against aerosol challenge

A DNA vaccine targeting VEE virus delivered by needle-free jet-injection protects macaques against aerosol challenge

We have previously shown that DNA vaccines expressing codon optimized alphavirus envelope glycoprotein genes protect both mice and nonhuman primates from viral challenge when delivered by particle-mediated epidermal delivery (PMED) or intramuscular (IM) electroporation (EP). Another technology with...

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Bibliographic Details
Main Authors: Adams, M.L (Author), Badger, C.V (Author), Bixler, S.L (Author), Hooper, J.W (Author), Kwilas, S.A (Author), Rossi, F.D (Author), Shoemaker, C.J (Author), Spiegel, E. (Author), Spik, K.W (Author), Suschak, J.J (Author), Twenhafel, N. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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