Plasma cell-free RNA profiling distinguishes cancers from pre-malignant conditions in solid and hematologic malignancies

Plasma cell-free RNA profiling distinguishes cancers from pre-malignant conditions in solid and hematologic malignancies

Cell-free RNA (cfRNA) in plasma reflects phenotypic alterations of both localized sites of cancer and the systemic host response. Here we report that cfRNA sequencing enables the discovery of messenger RNA (mRNA) biomarkers in plasma with the tissue of origin-specific to cancer types and precancerou...

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Bibliographic Details
Main Authors: Anur, P. (Author), Callahan, R. (Author), Civitci, F. (Author), Farsad, K. (Author), Kim, H.J (Author), Kirschbaum, C.W (Author), Naugler, W.E (Author), Ngo, T.T.M (Author), Roskams-Hieter, B. (Author), Spellman, P.T (Author), Spiliotopoulos, E. (Author), Thompson, R.F (Author), Wagner, J.T (Author)
Format: Article
Language:English
Published: Nature Research 2022
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