Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program

Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program

Deficiency of the immune checkpoint lymphocyte activation gene-3 (LAG3) protein is significantly associated with both elevated HDL-cholesterol (HDL-C) and myocardial infarction risk. We determined the association of genetic variants within ±500 kb of LAG3 with plasma LAG3 and defined LAG3-associated...

Full description

Bibliographic Details
Main Authors: Adrienne Cupples, L. (Author), Blackwell, T. (Author), Clish, C.B (Author), Conomos, M.P (Author), Cornell, E. (Author), Craig Johnson, W. (Author), Gerszten, R.E (Author), Guo, X. (Author), Jain, D. (Author), Kang, C. (Author), Lin, H. (Author), Liu, Y. (Author), Manichaikul, A. (Author), Papanicolaou, G.J (Author), Peter Durda, J. (Author), Rich, S.S (Author), Rodriguez, A. (Author), Rotter, J.I (Author), Taylor, K.D (Author), Tracy, R.P (Author), Vasan, R.S (Author), Yang, C. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items