Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients

RaTG13 is a close relative of SARS-CoV-2, the virus responsible for the COVID-19 pandemic, sharing 96% sequence similarity at the genome-wide level. The spike receptor binding domain (RBD) of RaTG13 contains a number of amino acid substitutions when compared to SARS-CoV-2, likely impacting affinity...

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Bibliographic Details
Main Authors: Bailey, D. (Author), Baxendale, H. (Author), Cantoni, D. (Author), Castillo-Olivares, J. (Author), Chan, A. (Author), Charleston, B. (Author), Elrefaey, A.M.E (Author), Heeney, J. (Author), Mayora-Neto, M. (Author), Nadesalingam, A. (Author), Newman, J. (Author), Smith, P. (Author), Temperton, N. (Author), Thakur, N. (Author), Vishwanath, S. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher