Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse

Suitable animal models are essential for translational research, especially in the case of complex, multifactorial conditions, such as obesity. The non-inbred mouse (Mus musculus) line Titan, also known as DU6, is one of the world’s longest selection experiments for high body mass and was previously...

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Main Authors: Aguilar-Pimentel, A. (Author), Becker, L. (Author), Brenmoehl, J. (Author), Calzada-Wack, J. (Author), Caton, V. (Author), de Angelis, M.H (Author), de-Diego, I. (Author), Forne, I. (Author), Fuchs, H. (Author), Gailus-Durner, V. (Author), Gerlini, R. (Author), Gille, B. (Author), Heiker, J.T (Author), Hoeflich, A. (Author), Imhof, A. (Author), Klein-Rodewald, T. (Author), Koch, F. (Author), Kuhla, A. (Author), Langhammer, M. (Author), Ludwig, C. (Author), Meng, C. (Author), Müller-Eigner, A. (Author), Palma-Vera, S. (Author), Peleg, S. (Author), Rathkolb, B. (Author), Reyer, H. (Author), Sanz-Moreno, A. (Author), Schoen, J. (Author), Venkatasubramani, A.V (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher