Statistical parametrization of cell cytoskeleton reveals lung cancer cytoskeletal phenotype with partial EMT signature

Epithelial–mesenchymal Transition (EMT) is a multi-step process that involves cytoskeletal rearrangement. Here, developing and using an image quantification tool, Statistical Parametrization of Cell Cytoskeleton (SPOCC), we have identified an intermediate EMT state with a specific cytoskeletal signa...

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Bibliographic Details
Main Authors: Alioscha-Perez, M. (Author), Basu, A. (Author), Dubinett, S.M (Author), Grosberg, A. (Author), Paul, M.K (Author), Sahli, H. (Author), Weiss, S. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher