Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer

Estrogen receptor (ER) positive breast cancer represents 75% of all breast cancers in women. Although patients with ER+ cancers receive endocrine therapies, more than 30% develop resistance and succumb to the disease, highlighting the need to understand endocrine resistance. Here we show an unexpect...

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Bibliographic Details
Main Authors: Ashitani, S. (Author), Endo, K. (Author), Matsuda, S. (Author), Muthuswamy, S.K (Author), Ohishi, M. (Author), Ohnishi, N. (Author), Saito, Y. (Author), Soga, T. (Author), Tomita, M. (Author), Ueda, K. (Author), Ueno, A. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher