Functional role of the Frizzled linker domain in the Wnt signaling pathway
The Wnt signaling pathway plays a critical role in the developmental and physiological processes of metazoans. We previously reported that the Frizzled4 (FZD4) linker domain plays an important role in Norrin binding and signaling. However, the question remains whether the FZD linker contributes to W...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Research
2022
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Online Access: | View Fulltext in Publisher |