Functional role of the Frizzled linker domain in the Wnt signaling pathway

The Wnt signaling pathway plays a critical role in the developmental and physiological processes of metazoans. We previously reported that the Frizzled4 (FZD4) linker domain plays an important role in Norrin binding and signaling. However, the question remains whether the FZD linker contributes to W...

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Bibliographic Details
Main Authors: Bang, I. (Author), Choi, H.-J (Author), Kang, C. (Author), Ko, S.-B (Author), Mihara, E. (Author), Park, Y. (Author), Roh, K. (Author), Takagi, J. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher