Low-dose sodium-glucose cotransporter 2 inhibitor ameliorates ischemic brain injury in mice through pericyte protection without glucose-lowering effects

Antidiabetic sodium-glucose cotransporter 2 (SGLT2) inhibitors have attracted attention for their cardiorenal-protective properties beyond their glucose-lowering effect. However, their benefits in ischemic stroke remain controversial. Here we show the effects of luseogliflozin, a selective SGLT2 inh...

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Bibliographic Details
Main Authors: Ago, T. (Author), Hidaka, M. (Author), Kitazono, T. (Author), Kiyohara, T. (Author), Nakamura, K. (Author), Shibahara, T. (Author), Takaki, H. (Author), Takashima, M. (Author), Wakisaka, M. (Author), Wakisaka, Y. (Author), Yamanaka, K. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher