Identification, synthesis and characterization of avanafil process impurities and determination by UPLC

Avanafil is a phosphodiesterase type 5 inhibitor which is used to treat erectile dysfunction in men. The process-related impurities of avanafil were investigated, and four kinds of impurities in several laboratory batches with a content of 0.29-1.63% were detected by the newly developed gradient ult...

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Bibliographic Details
Main Authors: Jin, Y. (Author), Liu, H. (Author), Liu, Z. (Author), Sun, Y. (Author), Wu, X. (Author), Yu, Z. (Author), Yuan, J. (Author), Zhao, M. (Author)
Format: Article
Language:English
Published: Royal Society of Chemistry 2022
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