Identification, synthesis and characterization of avanafil process impurities and determination by UPLC
Avanafil is a phosphodiesterase type 5 inhibitor which is used to treat erectile dysfunction in men. The process-related impurities of avanafil were investigated, and four kinds of impurities in several laboratory batches with a content of 0.29-1.63% were detected by the newly developed gradient ult...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Royal Society of Chemistry
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |