Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice

People with chronic obstructive pulmonary disease (COPD) are susceptible to respiratory infections which exacerbate pulmonary and/or cardiovascular complications, increasing their likelihood of death. The mechanisms driving these complications remain unknown but increased oxidative stress has been i...

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Bibliographic Details
Main Authors:	Almerdasi, S.A (Author), Bozinovski, S. (Author), Brassington, K. (Author), Chan, S.M.H (Author), De Luca, S.N (Author), Dobric, A. (Author), Mou, K. (Author), Oseghale, O. (Author), Selemidis, S. (Author), Seow, H.J (Author), Vlahos, R. (Author)
Format:	Article
Language:	English
Published:	NLM (Medline) 2022
Subjects:	acute exacerbations of chronic obstructive pulmonary disease adverse event animal Animals antioxidant Azoles Bagg albino mouse C57BL mouse cardiovascular disease chronic obstructive lung disease cigarette smoke cigarette smoking Cigarette Smoking complication ebselen endothelium human Humans influenza Influenza A virus Influenza, Human isoindole derivative Isoindoles lung Lung male Male metabolism Mice Mice, Inbred BALB C Mice, Inbred C57BL mouse Organoselenium Compounds organoselenium derivative pneumonia Pneumonia Pulmonary Disease, Chronic Obstructive pyrrole derivative tobacco Tobacco vascular dysfunction
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Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice

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