Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease

Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease

Chronic kidney disease (CKD) affects approximately 10-13% of the population worldwide and halting its progression is a major clinical challenge. Metabolic acidosis is both a consequence and a possible driver of CKD progression. Alkali therapy counteracts these effects in CKD patients, but underlying...

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Bibliographic Details
Main Authors: Amann, K. (Author), Bourgeois, S. (Author), Imenez Silva, P.H (Author), Joller, N. (Author), Mohebbi, N. (Author), Pastor Arroyo, E.M (Author), Russo, G. (Author), Sakiri, E. (Author), Wagner, C.A (Author), Yassini, N. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
acid-base balance
acidosis
Acidosis
alkali
alkali therapy
Alkalies
animal
Animals
chronic kidney disease
chronic kidney failure
complication
crystal nephropathy
female
Female
human
Humans
inflammation
Inflammation
kidney
Kidney
male
Male
metabolism
Mice
mouse
Renal Insufficiency, Chronic
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