Lawsone encapsulated polylactic-co-glycolic acid nanoparticles modified with chitosan-folic acid successfully inhibited cell growth and triggered apoptosis in Panc-1 cancer cells

Lawsone encapsulated polylactic-co-glycolic acid nanoparticles modified with chitosan-folic acid successfully inhibited cell growth and triggered apoptosis in Panc-1 cancer cells

The present research aims to encapsulate lawsone in polylactic-co-glycolic acid (PLGA) nanoparticles modified with folic acid (FA) and chitosan (CS) to study its anticancer effects against Panc-1 cells. The nanoparticles were analysed in means of shape/size and zeta potential index using scanning el...

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Bibliographic Details
Main Authors: Barati Naeeni, N. (Author), Ghafaripour, H. (Author), Homayouni Tabrizi, M. (Author), Karimi, E. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2023
Subjects:
Anticancer effects
Apoptosis induction
Cancer cells
Cell death
Chitosan
Diseases
Drug delivery
drug delivery systems
Drug-delivery systems
Dynamic light-scattering
Folic acids
Gene expression
Growth kinetics
High performance liquid chromatography
Lawsone
Light scattering
Medical nanotechnology
nanobiotechnology
nanomedicine
Nanoparticles
nanotechnology
Organic acids
Poly lactic-co-glycolic acid
polymer structure
Polymer structure
Polymerase chain reaction
Scanning electron microscopy
Scanning electrons
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