Cumulative use of salivary markers with an adaptive design improves detection of periodontal disease over fixed biomarker thresholds

Cumulative use of salivary markers with an adaptive design improves detection of periodontal disease over fixed biomarker thresholds

Objective: Aim was to analyze the diagnostic ability of cumulative risk score (CRS), which uses salivary levels of Porphyromonas gingivalis, interleukin (IL)-1β, and matrix metalloproteinase (MMP)-8 in an adaptive design, compared to previously reported thresholds of each marker alone. Materials and...

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Bibliographic Details
Main Authors: Gürsoy, U.K (Author), Könönen, E. (Author), Pussinen, P.J (Author), Salomaa, V. (Author), Syrjäläinen, S. (Author)
Format: Article
Language:English
Published: Taylor and Francis Ltd 2018
Subjects:
alveolar bone loss
Alveolar Bone Loss
biological marker
Biomarker
Biomarkers
human
Humans
interleukin 1beta
Interleukin-1beta
interleukin-1β
Matrix Metalloproteinase 8
matrix metalloproteinase-8
metabolism
microbiology
MMP8 protein, human
neutrophil collagenase
periodontal disease
Periodontal Diseases
periodontitis
porphyromonas gingivalis
Porphyromonas gingivalis
receiver operating characteristic
ROC Curve
saliva
Saliva
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