The PPARγ Agonist Pioglitazone Fails to Alter the Abuse Potential of Heroin, But Does Reduce Heroin Craving and Anxiety
Possibly through its effects on glia, the peroxisome proliferator-activated gamma receptor (PPARγ) agonist pioglitazone (PIO) has been shown to alter the effects of heroin in preclinical models. Until now, these results have not been assessed in humans. Heroin-dependent participants were randomized...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Routledge
2018
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Subjects: | |
Online Access: | View Fulltext in Publisher |