Suppression of glutathione system and upregulation of caspase 3-dependent apoptosis mediate rohypnol-induced gastric injury

Suppression of glutathione system and upregulation of caspase 3-dependent apoptosis mediate rohypnol-induced gastric injury

Objectives: This study investigated the impact of rohypnol on gastric tissue integrity.Methods: Forty male Wistar rats were randomized into control, low dose rohypnol-treated, high dose rohypnol-treated, low dose rohypnol-treated recovery and high dose rohypnol-treated recovery groups.Results: Rohyp...

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Bibliographic Details
Main Authors: Adegoke, T.E (Author), Ajayi, A.F (Author), Akhigbe, R.E (Author), Anyogu, D.C (Author), Hamed, M.A (Author), Oluwole, D.T (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
apoptosis
benzodiazepines
caspase 3
COX
drug abuse?
glutathione?
inflammation
oxidative stress
Rohypnol
stomach
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