Ficus deltoidea promotes bone formation in streptozotocin-induced diabetic rats

Ficus deltoidea promotes bone formation in streptozotocin-induced diabetic rats

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Context: Diabetes mellitus increases the risk of bone diseases including osteoporosis and osteoarthritis. We have previously demonstrated that Ficus deltoidea Jack (Moraceae) is capable of reducing hyperglycaemia. However, whether F. deltoidea could protect against diabetic osteoporosis remains to b...

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Bibliographic Details
Main Authors: Ahmad, H. (Author), Azmi, N.S (Author), Ebrahimi, M. (Author), Goh, Y.-M (Author), Md Dom, S. (Author), NoorMohamad Zin, N.S (Author), Samsulrizal, N. (Author)
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2021
Series:Pharmaceutical Biology
Subjects:
animal
animal experiment
animal model
animal tissue
Animals
antiosteoporotic activity
antioxidant
Article
BALP
bone density
Bone Density
bone development
bone histomorphometry
bone turnover
chondrocyte
controlled study
Diabetes
diabetes control
Diabetes Mellitus, Experimental
diabetic osteoporosis
diagnostic imaging
DPD
drug effect
enzyme linked immunosorbent assay
ex vivo study
experimental diabetes mellitus
fatty acids
feeding
femur
Ficus
Ficus deltoidea
Ficus deltoidea extract
hypertrophy
insulin
insulin blood level
isolation and purification
male
Male
metabolism
metformin
methanol
micro-computed tomography
micro-CT
Moraceae
morphometry
nonhuman
ossification
osteocalcin
Osteogenesis
osteoporosis
oxidative stress
physiology
plant extract
Plant Extracts
plant leaf
procedures
rat
Rats
Rats, Sprague-Dawley
sodium chloride
Sprague Dawley rat
streptozocin
Streptozocin
streptozotocin-induced diabetes mellitus
unclassified drug
X-Ray Microtomography
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